2015 Analysis of Emerging Nucleic Acid Testing Assays, and Strategic Profiles of Leading Suppliers

January 2015 | 549 pages | ID: 2F62F7C55E0EN
Venture Planning Group

Abstracts

This 549-page report presents an overview of the clinical significance and market needs for major current and emerging NAT assays, as well as extensive listings of companies developing and marketing innovative technologies and products. This report also presents strategic assessments of current and emerging suppliers of nucleic acid testing products, including their sales, product portfolios, marketing tactics, technological know-how, new products in R&D, collaborative arrangements and business strategies.

Contains 549 pages and 22 tables

Contents

Microbiology/Infectious Diseases

a. Overview
b. Major Infectious Diseases
  AIDS
    Structure and Composition
    Classification
    AIDS Origins
    Animal Lentivirus Systems
    Virus Receptors
    HIV Infections in Humans
      Pathogenesis and Pathology
    CD4T Lymphocytes and Memory Cells
    Monocytes and Macrophages
    Lymphoid Organs
    Neural Cells
    Viral Coinfections
      Clinical Findings
    Plasma Viral Load
    Pediatric AIDS
      Neurologic Disease
      Opportunistic Infections
      Cancer
    Immunity
      Virus Isolation
      Serology
      Viral Nucleic Acid/Antigen Detection
    Epidemiology
      Worldwide Spread of AIDS
      United States
      Routes of Transmission
    DNA Probes
      Overview
      Quantitative PCR
      In Situ PCR
      Needed Improvements
    Viral Load/Drug Resistance Testing
    Genotype and Phenotype Testing
    Blood Banking Considerations
      Adenovirus
    Background
    Diagnostic Tests O Vaccines and Drugs
    Adeno- Associated Viruses (AAV)
      Anthrax/Bacillus Anthracis
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Babesiosis
    Background
      BEA and Other Bartonella Diseases
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Chagas Disease
    Background
      Campylobacter
    Background
    Diagnostic Tests
      Culture Identification
    Vaccines and Drugs
      Chlamydia
    Background
      Chlamydia psittaci
      Chlmaydia pneumoniae
      Chlamydia trachomatis
    Diagnostic Tests
    Vaccines and Drugs
      Creutzfeldt- Jakob’s Disease
    Background
    Blood Transmission
    Diagnostic Tests
    Major Commercial and Academic Players
      Bayer
      Disease Sciences/Bio Tec Global
      Imperial College School of Medicine
      Ortho- Clinical Diagnostics
      Pall
      ProMetic Life Sciences
      Proteome Sciences/Idexx
      Q- One Biotech
      Serono
      U.S. Agricultural Research Service
    Drugs
    Vaccines
      Cytomegalovirus
    Background
      Chorioretinitis
      Gastrointestinal
      Central Nervous System Disease
    Diagnostic Tests
    Vaccines and Drugs
      Ebola Virus
    Background
      Epidemiology
      Clinical Syndromes
    Diagnostic Tests
    Vaccines and Drugs
      EchoVirus
    Background
      Acute Aseptic Meningitisis
      Encephalitis
      Exanthems
      Respiratory Disease
      Myopericarditis
      Neonatal Infections
    Diagnostic Tests
    Vaccines and Drugs
      Encephalitis
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Enteroviruses
    Background
    Diagnostic Tests
      Viral Isolation and Identification
      Antibody Tests
    Vaccines and Drugs
      Epstein- Barr Virus
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Gonorrhea
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Hepatitis
    Hepatitis A
    Hepatitis B
      Structure and Composition
      Replication
    Hepatitis C
    Hepatitis D (Delta)
    Hepatitis E
    Hepatitis G
    Hepatitis Infections Pathology
    Clinical Findings
    Laboratory Tests
      Hepatitis A
      Hepatitis B
      Hepatitis C
      Hepatitis D
      Hepatitis E
    Virus- Host Immune Reactions
    Epidemiology
      Hepatitis A
      Hepatitis B
      Hepatitis C
      Hepatitis D (Delta)
    Vaccines and Drugs
      Herpes Simplex Virus
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Legionella
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Lyme Disease
    Background
      Clinical Description
      Clinical Case Definition
      Laboratory Criteria for Diagnosis
      Case Classification
    Diagnostic Tests
    Vaccines and Drugs
      Malaria
      Mycoplasma
    Background
      Ureaplasma Urealyticum & Mycoplasma Hominis
    Diagnostic Tests
    Vaccines and Drugs
      Papillomaviruses/HPV
    Background
      HPV in Cancer
      Cervical Neoplasm
    Diagnostic Tests
    Vaccines and Drugs
      Prevention
      Parvovirus B19
    Background
      Microbiology
      Epidemiology
      Clinical Syndromes
      Erythema Infectiosum (Slapped Cheek)
      Adult Polyarthropathy
      Transient Aplastic Crisis
      Transient Pancytopenia
      Red Cell Aplasia in Immunocompromised
      Perinatal Infections
    Diagnostic Test
    Vaccines and Drugs
      Pneumonia
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Polyomaviruses
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Salmonellosis
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Shigellosis
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Streptococci
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Group A Streptococci
      Group B Streptococci
      Toxoplasmosis
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Tuberculosis
    Background
    Diagnostic Tests
      Microscopic Characteristics
      Cultural Characteristics
      Skin Tests
      MDRTB
    Vaccines and Drugs
      West Nile Virus
    Background
      Clinical Syndromes
    Diagnostic Tests
    Vaccines and Drugs
      Yersinia
    Background
    Diagnostic Tests
    Vaccines and Drugs
      Antibiotic Susceptibility

Cancer Testing

a. Overview
b. Major Cancer Types
  Prostate
  Lung
  Colon and Rectum
  Breast
  Skin
  Uterine
  Leukemia
  Oral
c. Oncogenes
    Abl/abl- bcr
    AIB1
    BCL- 2
    BRCA1
    CD44
    C- fos
    C- myb
    C- myc
    CYP17
    Erb- B
    HPC1
    N- myc
    P40
    P51
    P53
    PIK3CA
    PTI- 1
    Ras
    Reg
    Sis
    Src

Genetic Diseases

a. Overview
b. Nucleic Acid Amplification
c. Chromosome Imaging
d. Genomics Technologies
e. Proteomics Technologies
f. Current Pharmacogenomic Tests
g. Future Pharmacogenomic Testing
h. Major Diseases
  Achondroplasia
  Autosomal Dominant Polycystic Kidney Disease
  Cancer
  Cosmetogenomics
  Cystic Fibrosis
  Down's Syndrome
  Duchenne and Becker Muscular Dystrophy
  Factor V (Leiden)
  Factor IX Deficiency
  Fragile X Syndrome
  Heart Disease
  Hemochomatosis
  Hemophilia
  Huntington's Disease
  Maternal- Fetal Incompatibility
  Multiple Endocrine Neoplasia
  Phenylketonuria (PKU)
  Polycystic Kidney Disease (PKD)
  Prenatal Screening
  Retinitis Pigmentosa
  Retinoblastoma
  Sickle Cell Anemia
  Spinal Muscular Atrophy
  Vitamin B12 Metabolism
i. Social Issues and Concerns Forensic Testing
a. Overview
b. Multilocus and Single Locus Probes
  Multilocus Probes
  Single Locus Probes
  PCR and RFLP
c. The FBI
d. DNA Profile Data Banks
  U.S.A.
  U.K.
e. Judicial Implementation
f. Major Crime Categories
g. Factors Contributing to the DNA Probe Market Expansion
  Technology Availability
  Use of Hair as Evidence
h. Wildlife Forensics
Paternity Testing/HLA Typing
Other Applications
a. Disease Susceptibility Testing
b. Cardiovascular Diseases
c. Diabetes
d. Alzheimer's Disease
e. Periodontal Disease
f. Plasma Purification
g. Organ Transplantation
h. Water Contamination
i. Other

Competitive Profiles

Abbott
Affymetrix
Agilent
Applied Gene Technologies
Arca
Beckman Coulter/Danaher
Becton Dickinson
Biokit
BioMerieux
BioRad
Biotest
Caliper
Cepheid
Decode
Diadexus
Eiken
Enzo
Exact Sciences
Fujirebio
GenProbe
Hologic
Illumina
Innogenetics/Solvay
Kreatech
LiCor Biosciences
Life Technologies
Monogram Biosciences
Myriad Genetics
Nanogen/Elitech
Novartis
Orchid CellMark
OrthoClinical Diagnostics
Proteome Sciences
Qiagen
Roche
Scienion
Sequenom
Shimadzu
Siemens
Sierra Molecular
Takara Bio
Tecan Group

List Of Tables

LIST OF TABLES

Major Companies Developing or Marketing AIDS Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Adenovirus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Campylobacter Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Chlamydia Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing CMV Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing EBV Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Gonorrhea Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Hepatitis Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Herpes Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Legionella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Lyme Disease Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Mycoplasma Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Papilloma Virus Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Pneumonia Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Salmonella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Shigella Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Streptococci Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Toxoplasmosis Molecular Diagnostic And Other Direct Identification Tests
Major Companies Developing or Marketing Tuberculosis Molecular Diagnostic And Other Direct Identification Tests
Oncogenes Potential Application in Cancer Diagnosis
Major Companies Developing or Marketing Cancer Molecular Diagnostic Tests
Major Companies Developing or Marketing Molecular Diagnostic Test For Genetic Diseases