Worldwide Surgical Sealants, Glues, Wound Closure and Anti-Adhesion Markets, 2010-2015
This report details the complete range of sealants & glues technologies used in traumatic, surgical and other wound closure, from tapes, sutures and staples to hemostats, fibrin sealants/glues and medical adhesives. The report details current clinical and technology developments in this huge and rapidly growing worldwide market, with data on products in development and on the market; market size and forecast; competitor market shares; competitor profiles; and market opportunity.
This report is a market and technology assessment and forecast of surgical sealants, glues, hemostasis, other wound closure and anti-adhesion. The report details the current and emerging products, technologies and markets involved in wound closure and sealing using sutures and staples, tapes, hemostats, fibrin and sealant products, medical adhesives and products to prevent surgical adhesions. With full year actual data from 2009 and, for many companies, two quarters of actual data from 2010, the report provides a worldwide forecast to 2015 of the markets for these technologies, with particular emphasis on the market impact of new technologies through the coming decade. The report provides specific forecasts and shares of the worldwide market by segment for the U.S., Europe (United Kingdom, German, France, Italy, BeNeLux), Latin America, Japan, Korea and Rest of World.
The report provides background data on the surgical, disease and traumatic wound patient populations targeted by current technologies and those under development, and the current clinical practices in the management of these patients, including the dynamics among the various clinical specialties or subspecialties vying for patient population and facilitating or limiting the growth of technologies.
The report establishes the current worldwide market size for major technology segments as a baseline for and projecting growth in the market over a five-year forecast. The report also assesses and projects the composition of the market as technologies gain or lose relative market performance over this period.
This report is a market and technology assessment and forecast of surgical sealants, glues, hemostasis, other wound closure and anti-adhesion. The report details the current and emerging products, technologies and markets involved in wound closure and sealing using sutures and staples, tapes, hemostats, fibrin and sealant products, medical adhesives and products to prevent surgical adhesions. With full year actual data from 2009 and, for many companies, two quarters of actual data from 2010, the report provides a worldwide forecast to 2015 of the markets for these technologies, with particular emphasis on the market impact of new technologies through the coming decade. The report provides specific forecasts and shares of the worldwide market by segment for the U.S., Europe (United Kingdom, German, France, Italy, BeNeLux), Latin America, Japan, Korea and Rest of World.
The report provides background data on the surgical, disease and traumatic wound patient populations targeted by current technologies and those under development, and the current clinical practices in the management of these patients, including the dynamics among the various clinical specialties or subspecialties vying for patient population and facilitating or limiting the growth of technologies.
The report establishes the current worldwide market size for major technology segments as a baseline for and projecting growth in the market over a five-year forecast. The report also assesses and projects the composition of the market as technologies gain or lose relative market performance over this period.
Contents
EXECUTIVE SUMMARYIntroduction
Demographic trends
Consumer-Driven Product Selection
Mechanisms of Tissue Repair
Commercial Imperatives
Industry Consolidation
Clinical Caseload
Market Segmentation and Dynamics
New Surgical Techniques Drive Market Opportunity
The Uses of Adjunctive Surgical Closure and Securement Products
Product Development History
Evolution of Commercial Markets for Sealants and Adhesives
Overview of Company Strategies
SECTION 1: CLINICAL NEED, CASELOAD, AND PROCEDURE VOLUME
1.1 Anatomy and Physiology of Tissue Repair
1.2 The Skin
1.3 Internal Tissues and Organs
1.4 Wound Classification and Types
1.4.1 Classification by Morphology and Severity
1.4.2 Wound Classification by Cause
1.4.3 Surgical Wounds
1.5 Caseload
1.5.1 Cardiovascular
1.5.1.1 Coronary Heart Disease
1.5.1.2 Dysfunctional Heart Valves
1.5.1.3 Peripheral Vascular Disorders
1.5.1.4 Abnormal Aortic Aneurysms
1.5.1.5 Drivers of Caseloads for Cardiac Surgery
1.5.2 Neurological
1.5.2.1 Stroke
1.5.2.2 Parkinson’s Disease
1.5.2.3 Epilepsy
1.5.2.4 Traumatic Injury
1.5.2.5 Peripheral Nerve Treatment
1.5.2.6 Neurology Drivers
1.5.3 Orthopedic
1.5.3.1 Hip Replacements
1.5.3.2 Knee Replacements
1.5.3.3 Cartilage Repair
1.5.3.4 Ligament Damage
1.5.3.5 Bone Grafting
1.5.3.6 Vertebral Disc Repair
1.5.3.7 Drivers of Orthopedic Surgery
1.5.4 Urological
1.5.4.1 Incontinence
1.5.4.2 Drivers of Urological Surgery
1.5.5 Skin
1.5.5.1 Burns
1.5.5.2 Pressure Ulcers
1.5.5.3 Diabetic Ulcers
1.5.5.4 Venous Ulcers
1.5.5.5 Plastic Surgery
1.6 The Role of Modern Sealant, Securement and Hemostatic Products in Surgery
1.6.1 Fibrin Sealants
1.6.2 High-Strength Glues
SECTION 2: SCIENCE, TECHNOLOGY, DEVELOPMENT, CLINICAL AND REGULATORY CHALLENGES
2.1 Tissue Healing
2.1.1 Hemostasis
2.1.2 Proliferation and Maturation
2.1.3 Factors That Affect Healing
2.2 Product Development
2.3 Development Timelines
2.3.1 Collagen and Thrombin Combination
2.3.2 Polyethylene Glycol Polymer (PEG)
2.3.3 Albumin Cross-Linked with Glutaraldehyde
2.3.4 Delivery Systems
2.4 Cost-Effectiveness
2.5 Regulatory Challenges
2.5.1 Approval Processes .
2.5.2 History of Product Development
2.5.3 Regulatory Aspects
SECTION 3: PRODUCTS, TECHNOLOGIES, AND FORECAST OPPORTUNITY
3.1 Overview
3.2 Development Timeline
3.3 Sutures, Staples, and Other Mechanical Closure Devices
3.3.1 Sutures, Staples and Mechanical Closure Competitors and Products
3.3.2 Sutures, Staples and Mechanical Closure Products in Development
3.3.3 Sutures, Staples and Mechanical Closure Market Analysis and Forecast
3.4 Tapes
3.4.1 Medical Tape Competitors and Products
3.4.2 Medical Tape Market Analysis and Forecast
3.5 Hemostats
3.5.1 Hemostat Competitors and Products
3.5.2 Hemostat Products in Development
3.5.3 Hemostat Market Analysis and Forecasts
3.6 Fibrin and Other Sealant Products
3.6.1 Fibrin and Other Sealant Competitors and Products
3.6.2 Fibrin and Other Sealant Products in Development
3.6.3 Fibrin and Sealant Market Analysis and Forecasts
3.7 High-Strength Medical Adhesives
3.7.1 High-Strength Medical Adhesive Competitors and Products
3.7.2 High-Strength Medical Adhesive Products in Development
3.7.3 High-Strength Medical Adhesive Market Analysis and Forecasts
3.8 Post-Surgical Adhesion Prevention
3.8.1 Post-Surgical Adhesion Prevention Competitors and Products
3.8.2 Post-Surgical Adhesion Prevention Products in Development
3.8.3 Post-Surgical Adhesion Prevention Market Analysis and Forecasts
3.9 Wound Closure and Securement Markets: Global and Regional Analysis
3.9.1 Americas
3.9.1.1 United States
3.9.1.2 Latin America
3.9.2 Japan and Korea
3.9.3 Europe
3.9.4 Rest of World
3.10 Worldwide Markets By Country and Segment
SECTION 4: COMPANY PROFILES
3DM, INC. (3D-MATRIX, LTD.)
3M
Abbott Laboratories
AccessClosure, Inc.
Adhezion Biomedical, LLC
Advanced Medical Solutions plc/Medlogic Global
Aeris Therapeutics
Angiotech Pharmaceuticals, Inc.
Anika Therapeutics, Inc.
ARC Pharmaceuticals
Arch Therapeutics, Inc.
ArthroCare Corporation
Aso LLC
Aspen Surgical Products
Avery Dennison
B. Braun (Braun Melsungen AG
Baxter International Inc.
Berlin Heart GmbH
Bernsco Surgical Supply (George Tiemann & Co.)
Biocoral Inc.
BIOSTER a.s.
BSN Medical
C.R. Bard (Bard Medical, Davol)
Cardiva Medical, Inc.
Ceremed, Inc.
Chemence Medical
Cohera Medical, Inc.
Collagen Matrix, Inc.
Coloplast A/S
Covidien Ltd.
CryoLife Inc.
CSIRO PhotoMedical Technologies
CSL Behring
CSMG Technologies, Inc. (Live Tissue Connect, Inc.)
CuraMedical BV
Derma Sciences, Inc.
DuPont Applied BioSciences
Entegrion, Inc.
FibroGen, Inc.
Fidia Advanced Biopolymers
FzioMed Inc.
Gelita Medical BV
GEM srl
Genzyme Biosurgery Inc.
GluStitch
Graceduty Company Limited
Hartmann Group/ Hartmann USA
Harvest Technologies Corporation
HemCon Medical Technologies, Inc.
Hemostasis, LLC
Human BioSciences, Inc.
HyperBranch Medical Technology, Inc.
Incisive Surgical, Inc.
Innovasa Corporation
Integra Lifesciences Corporation
Johnson & Johnson (Ethicon, Inc., Ethicon Endo-Surgery, Inc.)
Kaketsuken (Chemo-Sero-Therapeutic Research Institute)
Kensey Nash Corporation
Kimberly-Clark Health Care
Kinetic Concepts, Inc.
King Pharmaceuticals, Inc.
Kookbo Chemicals Co., Ltd. (KB Chem.)
Laboratoires Urgo (Urgo Medical)
LifeBond Ltd.
Lohmann & Rauscher
Marine Polymer Technologies
Medafor, Inc.
MedTrade Products, Ltd.
Meyer-Haake GmbH Medical Innovations
Molnlycke Health Care AB
Morris Innovative
Motex Healthcare Corp.
NeatStitch Ltd.
Nycomed
Ocular Therapeutix, Inc.
Omrix Biopharmaceuticals Inc.
Pfizer Inc.
Pharming Group NV
Piramal Healthcare
Plasma Technologies, Inc.
Pluromed, Inc.
Polyganics
Polyheal Ltd.
ProFibrix BV
Protein Polymer Technologies, Inc.
Resorba Wundversorgung GmbH & Co. KG
Scion Cardio-Vascular, Inc.
Sea Run Holdings
Smith & Nephew plc
St. Jude Medical
Starch Medical, Inc.
Synovis Life Technologies
SyntheMed, Inc.
Teleflex Medical
ThermoGenesis Corporation
Thrombotargets Corp.
Tissuemed Ltd.
Vascular Solutions, Inc.
Vectura Group plc
Vivostat A/S
Wound Care Technologies, Inc.
Z-Medica Corporation
Zimmer
ZymoGenetics, Inc.
APPENDIX: LIST OF COMPANIES
LIST OF EXHIBITS
Exhibit ES-1: Recent Acquisitions in the Securement Segment
Exhibit ES-2: Select Introducers of New Securement Technologies
Exhibit ES-3: Definition of Surgical Closure and Securement Products
Exhibit ES-4: Incidence of Two Types of Surgical Procedures In the United States with High Requirement for Adjunctive Products for Surgical Closure and Securement
Exhibit ES-5: U.S. FDA-Approved Uses of Sealants, Glues and Hemostats
Exhibit ES-6: Selected Synthetic and Biological Sealant Competitors (Non-Fibrin Sealants)
Exhibit ES-7: Selected High-Strength Adhesive Companies and Their Strategies
Exhibit ES-8: Selected Sealant Product Companies and Their Strategies
Exhibit ES-9: Worldwide Growth in the Securement and Closure Market, 2010-2015 (Millions)
Exhibit 1-1: Skin Structure Illustrating Major Organelles and Skin Layers
Exhibit 1-2: Classification of Wounds by Morphology
Exhibit 1-3: Severity Classification of Wounds
Exhibit 1-4: Wound Classification by Etiology
Exhibit 1-5: Prevalence of Different Wound Types, 2009
Exhibit 1-6: Criteria for Adjunctive Use of Hemostats, Sealants, Glues and Adhesion Prevention Products in Surgery
Exhibit 1-7: Surgical Procedures with Potential for the Use of Hemostats, Sealants, Glues and Adhesion Prevention Products, Worldwide (Millions). 2009
Exhibit 1-8: Prevalence of Common Cardiovascular Diseases, 2006 (000)
Exhibit 1-9: Potential for Neurological Applications, Prevalence of Applicable Disorders (000)
Exhibit 1-10: Potential for Orthopedic Applications, Frequency of Major Surgical Interventions (000)
Exhibit 1-11: Potential for Urological Applications, Prevalence of Applicable Disorders (000)
Exhibit 1-12: Potential for Dermal Repair, Prevalence of Applicable Disorders (000)
Exhibit 1-13: Applications of Fibrin and Other Sealants
Exhibit 1-14: Surgical Procedures Using Fibrin and Other Sealant Products
Exhibit 1-15: Surgical Indications for High-Strength Glues
Exhibit 2-1: Factors That Affect Wound Healing
Exhibit 2-2: Timescales for Development of Closure and Sealant Products
Exhibit 2-3: Variables Associated With Clinical Evaluation of Closure and Securement and Related Products
Exhibit 3-1: Competitors in the Market for Sutures, Staples and Other Mechanical Closure Devices
Exhibit 3-2: Worldwide Market Forecast for Sutures, Staples and Other Mechanical Closure Devices, 2010-2015, USD Million
Exhibit 3-3: Worldwide Market for Sutures, Staples and Other Mechanical Closure Devices, Competitor Market Shares, 2009, USD Million
Exhibit 3-4: Competitors in the Market for Medical Tapes
Exhibit 3-5: Worldwide Market Forecast for Medical Tapes, 2010-2015, USD Million
Exhibit 3-6: Worldwide Market for Medical Tapes, Competitor Market Shares, 2009, USD Million
Exhibit 3-7: Competitors in the Market for Hemostats
Exhibit 3-8: Worldwide Market Forecast for Hemostats, 2010–2015, USD Million
Exhibit 3-9: Worldwide Market for Hemostats, Competitor Market Shares, 2009, USD Million
Exhibit 3-10: Competitors in the Market for Fibrin and Other Sealants
Exhibit 3-11: Worldwide Market Forecast for Fibrin and Other Sealants, 2010-2015, USD Million
Exhibit 3-12: Worldwide Market for Fibrin and Other Sealants, Competitor Market Shares, 2009, USD Million
Exhibit 3-13: Competitors in the Market for High-Strength Medical Adhesives
Exhibit 3-14: Worldwide Market Forecast for High-Strength Medical Adhesives, 2010-2015, USD Million
Exhibit 3-15: Worldwide Market for High-Strength Medical Adhesives, Competitor Market Shares, 2009, USD Million
Exhibit 3-16: Competitors in the Market for Post-Surgical Adhesion Prevention
Exhibit 3-17: Worldwide Market Forecast for Post-Surgical Adhesion Prevention, 2010-2015, USD Million
Exhibit 3-18: Worldwide Market for Post-Surgical Adhesion Prevention, Competitor Market Shares, 2009, USD Million
Exhibit 3-19: Size and Growth of Wound Closure and Securement Market, World and Selected Countries, 2009
Exhibit 3-20: Wound Closure Market by Product Segments: The Major American Countries, 2009, USD Million
Exhibit 3-21: Wound Closure Market by Product Segments, Japan, 2009, USD Millions
Exhibit 3-22: Wound Closure Market by Product Segments, Korea, 2009, USD Millions
Exhibit 3-23: Wound Closure Market by Product Segments, Major European Countries, 2009, USD Millions
Exhibit 3-24: Wound Closure Market by Product Segments, Rest of World, 2009, USD Millions
Exhibit 3-25: Growth Forecast for Closure and Securement Market, 2010-2015, USD Millions
Exhibit 4-1: Johnson & Johnson Wound Closure Products Skip to top