2015-2019 US Transfusion Diagnostics Market: Supplier Shares, Sales Forecasts, Innovative Technologies, Competitive Strategies
Complete report $9,700. DataPack (test volumes, sales forecasts, supplier shares) $6,300. 2015-2019 US Transfusion Diagnostics Markett is a new strategic analysis prepared by VPGMarketResearch in order to help current suppliers and potential market entrants identify and evaluate emerging opportunities and assist industry executives in developing effective business, new product development and marketing strategies. RationaleDuring the nextfive years, the US blood banking market is expected to undergo significant transformation, which will result from the convergence of several trends, including more stringent regulations; advances in diagnostic technologies, IT, system engineering and automation; and intensifying competition. Some segments will start resembling commodity markets, where product positioning and differentiation are more critical than underlying technology. The changes in the marketplace will create exciting opportunities for new instruments and reagent systems, as well as auxiliary products, such as specimen preparation devices, controls, calibrators, and innovative IT applications. Strategic Recommendations- New product development opportunities with significant market appeal. - Alternative market penetration strategies. - Potential market entry barriers and risks. The report explores future marketing and technological trends in the US; provides estimates of the test volume, instrument placements and sales; compares features of major automated and semi-automated analyzers; profiles leading and emerging competitors; and identifies specific product and market opportunities facing suppliers during the next ten years. Blood Typing and Grouping TestsABO, Antibody Panels, Antibody Screening/Indirect Antiglobulin, Antigen Typing (C, c, Duffy, E, e, I, i, Kell, Kidd, Le a, b, MN, P, S, s), Antiglobulin (Direct, C3 + IgG, IgG, C3), Crossmatching (Immediate Spin, Full Crossmatch), Rh (D, Du). Infectious Disease Screening TestsAIDS (HIV NAT, HIV-1/2), Cytomegalovirus,Hepatitis (HAV NAT, HBV NAT, HBs Ag, Anti-HBc, HCV NAT, HCV, ALT/SGPT), HTLV-I/II, Parvovirus B19 NAT, Syphilis, West Nile Virus NAT. Sales and Market Share AnalysisSales and market share estimates of leadingsuppliers of blood banking of reagentsand instruments, by individual product. Competitive AssessmentsStrategic assessments of major suppliers and emerging market entrants, including their sales,product portfolios, marketing tactics, and newproducts in R&D. Market Segmentation Analysis- Comprehensive market segmentationanalysis, including review of the marketdynamics, trends, structure, size, growth,and key suppliers. - Test volume and sales forecasts for over 40 blood banking tests, including NAT, by market segment:- Blood Centers- Plasma Fractionation Facilities- Hospitals- Commercial/Private Laboratories- Military Blood BanksCurrent and Emerging Products- Analysis of current and emerging blood banking tests. - Review of automated and semi-automatedanalyzers, including their operatingcharacteristics, features, and selling prices. Technology Review- Assessment of current and emerging technologies,and their potential applications for the blood banking market. - Comprehensive lists of companies developingor marketing new technologies and products by test. Contains 460 pages and 53 tables
I. INTRODUCTION
II. MAJOR PRODUCT DEVELOPMENT OPPORTUNITIES
A. Blood Typing and Grouping
B. Infectious Disease Screening
C. Auxiliary
III. ALTERNATIVE MARKET PENETRATION STRATEGIES
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
IV. POTENTIAL MARKET ENTRY BARRIERS AND RISKS
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
V. WORLDWIDE TECHNOLOGY AND MARKET OVERVIEW
A. Major Blood Typing, Grouping and Infectious Disease Screening Tests
1. Blood Typing and Grouping Tests
a. ABO
b. Antibody Panels
c. Antibody Screening
d. Antigen Typing
e. Antiglobulin Test
f. Crossmatch
g. HLA Typing
h. Rh
i. Other Blood Groups
2. Infectious Disease Screening Tests
a. AIDS
Structure and Composition
Classification
Origin of AIDS
Animal Lentivirus Systems
Virus Receptors
HIV Infections in Humans
Pathogenesis & Pathology
Overview of Course of HIV Infection
CD4T Lymphocytes and Memory Cells
Monocytes and Macrophages
Lymphoid Organs
Neural Cells
Viral Coinfections
Clinical Findings
Plasma Viral Load
Pediactric AIDS
Neurologic Disease
Opportunistic Infections
Protozoa
Fungi
Bacteria
Viruses
Cancer
Immunity
Laboratory Diagnosis
Virus Isolation
Serology
Detection of Viral Nucleic Acid or Antigens
Epidemiology
Worldwide Spread of AIDS
United States
Routes of Transmission
Prevention, Treatment, And Control
Antiviral Drugs
Vaccines Against HIV
Transmission of HIV in Blood Products
HIV Transmission in Transplant and Artificial Insemination Recipients
Diagnostic Tests
Enzyme Immunoassay Interpretation
Specificity, Sensitivity, and Predictive Value of Enzyme Immunoassay
Competition Assays
Western Blot Technique
Immuno-Fluorescence Assay (IFA)
Radioimmunoprecipitation
HIV-1/HIV-2 Combination Testing
Methods of HIV-Antigen Detection
Antigen Assays and Blood Screening
Urine Tests
DNA Probes
Overview
Quantitative Polymerase Chain Reaction
In Situ PCR
Needed Improvements
Viral Load/Drug Resistance Testing
Genotype and Phenotype Testing
Blood Banking Considerations
b. Hepatitis
Hepatitis A
Hepatitis B
Structure and Composition
Replication of Hepatitis B Virus
Hepatitis C
Hepatitis D (Delta Hepatitis)
Hepatitis E
Hepatitis G
Hepatitis Virus Infections In Humans
Pathology
Clinical Findings
Laboratory Features
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
Virus-Host Immune Reactions
Epidemiology
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D (Delta Agent)
Vaccines and Drugs
c. Cytomegalovirus
Background
Chorioretinitis
Gastrointestinal
Central Nervous System Disease
Diagnostic Tests
Vaccines and Drugs
d. Syphilis
Background
Diagnostic Tests
Vaccines and Drugs
e. West Nile Virus
Background
Clinical Syndromes
Diagnostic Tests
Vaccines and Drugs
f. Parvovirus B19
Microbiology
Epidemiology
Clinical Syndromes
Erythema Infectiosum Slapped (cheek)
Adult Polyarthropathy
Transient Aplastic Crisis
Transient Pancytopenia
Red Cell Aplasia in the Immunocompromised
Perinatal Infections
Diagnosis
Treatment
g. Creutzfeldt-Jakob’s Disease
Background
Transmission
Diagnostic Tests
Major Commercial and Academic Players
Bayer
Disease Sciences/BioTec Global
Imperial College School of Medicine
Ortho-Clinical Diagnostics
Pall
ProMetic Life Sciences
Proteome Sciences/Idexx
Q-One Biotech
Serono
U.S. Agricultural Research Service
Drugs
Vaccines
h. Malaria
i. Chagas Disease
j. Babesiosis
3. Pathogen Reduction
4. Leukocyte Reduction
Background
Methods
B. Instrumentation Review: Operating Characteristics, Features and Selling Prices of Leading Automated and Semiautomated Analyzers Manufactured by:
Abbott
Beckman Coulter/Danaher
Bio-Rad
BioMerieux
Gen-Probe
Grifols
Immucor
Nanosphere
Ortho-Clinical Diagnostics
Roche
Sarstedt
Siemens
Tecan
C. Major in Vitro Diagnostic Technologies And Their Potential Applications
1. Molecular Diagnostics
a. Overview
b. NAT
2. Monoclonal and Polyclonal Antibodies
3. Immunoassays
a. Technological Principle
b. Chemiluminescence
c. Enzyme Immunoassays (EIA)
Overview
ELISA
EMIT
Electrochemical
d. Radioimmunoassays (RIA)
e. Immunoprecipitation
f. Affinity Chromatography
4. Microtitration Plates
5. IT and Automation
6. Lasers
7. Robotics
8. Synthetic Red Cell Substitutes
9. Genetically Engineered Blood Components
a. Albumin
b. Factor VIII
c. Alpha-2 Antiplasmin
d. Antithrombin III
e. Factor IX
f. Von Willebrand's Factor
g. Fibrinogen
h. t-PA
10. Blood Preservation
11. Autologous Blood Transfusion/Freezing
VI. U.S.A.
A. Executive Summary
B. Business Environment
1. Overview
2. Health Care Expenditures
3 Cost Consciousness
4. Industry Consolidation
5. Managed Care
6. Hospitals
7. Admissions
8. Length of Stay
9. Industry Diversification
10. Physician Demographics
11. Population Aging
a. Chronic Illnesses
b. Disease Incidence
c. Susceptibility to Latrogenesis
d. Multiple Illness Cases
12. Laboratory Regulations
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares
VII. COMPETITIVE ASSESSMENTS
Abbott
Beckman Coulter/Danaher
Becton Dickinson
Biokit
BioMerieux
Bio-Rad
Diagast
DiaSorin
Fujirebio/Innogenetics
Hologic/Gen-Probe
Grifols
Immucor
Novartis Diagnostics
Ortho-Clinical Diagnostics
Orchid CellMark
Proteome Sciences
Quest Diagnostics
Quidel
Roche
Siemens
Tecan
VIII. APPENDIX: ASSUMED CURRENCY EXCHANGE RATES
II. MAJOR PRODUCT DEVELOPMENT OPPORTUNITIES
A. Blood Typing and Grouping
B. Infectious Disease Screening
C. Auxiliary
III. ALTERNATIVE MARKET PENETRATION STRATEGIES
A. Internal Development
B. Collaborative Arrangements
C. University Contracts
IV. POTENTIAL MARKET ENTRY BARRIERS AND RISKS
A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
V. WORLDWIDE TECHNOLOGY AND MARKET OVERVIEW
A. Major Blood Typing, Grouping and Infectious Disease Screening Tests
1. Blood Typing and Grouping Tests
a. ABO
b. Antibody Panels
c. Antibody Screening
d. Antigen Typing
e. Antiglobulin Test
f. Crossmatch
g. HLA Typing
h. Rh
i. Other Blood Groups
2. Infectious Disease Screening Tests
a. AIDS
Structure and Composition
Classification
Origin of AIDS
Animal Lentivirus Systems
Virus Receptors
HIV Infections in Humans
Pathogenesis & Pathology
Overview of Course of HIV Infection
CD4T Lymphocytes and Memory Cells
Monocytes and Macrophages
Lymphoid Organs
Neural Cells
Viral Coinfections
Clinical Findings
Plasma Viral Load
Pediactric AIDS
Neurologic Disease
Opportunistic Infections
Protozoa
Fungi
Bacteria
Viruses
Cancer
Immunity
Laboratory Diagnosis
Virus Isolation
Serology
Detection of Viral Nucleic Acid or Antigens
Epidemiology
Worldwide Spread of AIDS
United States
Routes of Transmission
Prevention, Treatment, And Control
Antiviral Drugs
Vaccines Against HIV
Transmission of HIV in Blood Products
HIV Transmission in Transplant and Artificial Insemination Recipients
Diagnostic Tests
Enzyme Immunoassay Interpretation
Specificity, Sensitivity, and Predictive Value of Enzyme Immunoassay
Competition Assays
Western Blot Technique
Immuno-Fluorescence Assay (IFA)
Radioimmunoprecipitation
HIV-1/HIV-2 Combination Testing
Methods of HIV-Antigen Detection
Antigen Assays and Blood Screening
Urine Tests
DNA Probes
Overview
Quantitative Polymerase Chain Reaction
In Situ PCR
Needed Improvements
Viral Load/Drug Resistance Testing
Genotype and Phenotype Testing
Blood Banking Considerations
b. Hepatitis
Hepatitis A
Hepatitis B
Structure and Composition
Replication of Hepatitis B Virus
Hepatitis C
Hepatitis D (Delta Hepatitis)
Hepatitis E
Hepatitis G
Hepatitis Virus Infections In Humans
Pathology
Clinical Findings
Laboratory Features
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
Hepatitis E
Virus-Host Immune Reactions
Epidemiology
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D (Delta Agent)
Vaccines and Drugs
c. Cytomegalovirus
Background
Chorioretinitis
Gastrointestinal
Central Nervous System Disease
Diagnostic Tests
Vaccines and Drugs
d. Syphilis
Background
Diagnostic Tests
Vaccines and Drugs
e. West Nile Virus
Background
Clinical Syndromes
Diagnostic Tests
Vaccines and Drugs
f. Parvovirus B19
Microbiology
Epidemiology
Clinical Syndromes
Erythema Infectiosum Slapped (cheek)
Adult Polyarthropathy
Transient Aplastic Crisis
Transient Pancytopenia
Red Cell Aplasia in the Immunocompromised
Perinatal Infections
Diagnosis
Treatment
g. Creutzfeldt-Jakob’s Disease
Background
Transmission
Diagnostic Tests
Major Commercial and Academic Players
Bayer
Disease Sciences/BioTec Global
Imperial College School of Medicine
Ortho-Clinical Diagnostics
Pall
ProMetic Life Sciences
Proteome Sciences/Idexx
Q-One Biotech
Serono
U.S. Agricultural Research Service
Drugs
Vaccines
h. Malaria
i. Chagas Disease
j. Babesiosis
3. Pathogen Reduction
4. Leukocyte Reduction
Background
Methods
B. Instrumentation Review: Operating Characteristics, Features and Selling Prices of Leading Automated and Semiautomated Analyzers Manufactured by:
Abbott
Beckman Coulter/Danaher
Bio-Rad
BioMerieux
Gen-Probe
Grifols
Immucor
Nanosphere
Ortho-Clinical Diagnostics
Roche
Sarstedt
Siemens
Tecan
C. Major in Vitro Diagnostic Technologies And Their Potential Applications
1. Molecular Diagnostics
a. Overview
b. NAT
2. Monoclonal and Polyclonal Antibodies
3. Immunoassays
a. Technological Principle
b. Chemiluminescence
c. Enzyme Immunoassays (EIA)
Overview
ELISA
EMIT
Electrochemical
d. Radioimmunoassays (RIA)
e. Immunoprecipitation
f. Affinity Chromatography
4. Microtitration Plates
5. IT and Automation
6. Lasers
7. Robotics
8. Synthetic Red Cell Substitutes
9. Genetically Engineered Blood Components
a. Albumin
b. Factor VIII
c. Alpha-2 Antiplasmin
d. Antithrombin III
e. Factor IX
f. Von Willebrand's Factor
g. Fibrinogen
h. t-PA
10. Blood Preservation
11. Autologous Blood Transfusion/Freezing
VI. U.S.A.
A. Executive Summary
B. Business Environment
1. Overview
2. Health Care Expenditures
3 Cost Consciousness
4. Industry Consolidation
5. Managed Care
6. Hospitals
7. Admissions
8. Length of Stay
9. Industry Diversification
10. Physician Demographics
11. Population Aging
a. Chronic Illnesses
b. Disease Incidence
c. Susceptibility to Latrogenesis
d. Multiple Illness Cases
12. Laboratory Regulations
C. Market Structure
D. Market Size, Growth and Major Suppliers’ Sales and Market Shares
VII. COMPETITIVE ASSESSMENTS
Abbott
Beckman Coulter/Danaher
Becton Dickinson
Biokit
BioMerieux
Bio-Rad
Diagast
DiaSorin
Fujirebio/Innogenetics
Hologic/Gen-Probe
Grifols
Immucor
Novartis Diagnostics
Ortho-Clinical Diagnostics
Orchid CellMark
Proteome Sciences
Quest Diagnostics
Quidel
Roche
Siemens
Tecan
VIII. APPENDIX: ASSUMED CURRENCY EXCHANGE RATES
LIST OF TABLES
Major Companies Developing or Marketing Blood Typing and Grouping Tests
Major Companies Developing or Marketing HLA Typing Tests
Major Companies Developing or Marketing AIDS Tests
Major Companies Developing or Marketing Hepatitis Tests
Major Companies Developing or Marketing CMV Tests
Major Companies Developing or Marketing Syphilis Tests
Major Companies Developing or Marketing Blood Bank Analyzers
Executive Summary Table: U.S.A., Total Blood Bank Test Volume and Reagent Sales Forecast by Test Category
U.S.A., Estimated Number of Inpatient and Ambulatory Surgeries
U.S.A., Facilities Performing Blood Bank Tests by Market Segment
U.S.A., Hospital Laboratories Performing Blood Bank Tests by Bed Size
U.S.A., Commercial/Private Laboratories Performing Blood Bank Tests by Annual Test Volume Forecast
U.S.A., Facilities Collecting Whole Blood And Plasma by Market Forecast Segment
U.S.A., Whole Blood and Plasma Collections By Market Forecast Segment
U.S.A., All Market Segments Blood Typing and Grouping Test Volume by Market Forecast Segment
U.S.A., All Market Segments Blood Typing And Grouping Test Volume Forecast
U.S.A., Hospital Laboratories Blood Typing and Grouping Test Volume Forecast
U.S.A., Community and Regional Blood Centers Blood Typing and Grouping Test Volume Forecast
U.S.A., Commercial/Private Laboratories Blood Typing and Grouping Test Volume Forecast
U.S.A., Plasma Fractionation Centers Blood Typing and Grouping Test Volume Forecast
U.S.A., Military Blood Banks Blood Typing and Grouping Test Volume Forecast
U.S.A., All Market Segments Infectious Disease Screening Test Volume Forecast By Market Segment
U.S.A., All Market Segments Infectious Disease Screening Test Volume Forecast
U.S.A., Community and Regional Centers Infectious Disease Screening Test Volume Forecast
U.S.A., Plasma Fractionation Centers Infectious Disease Screening Test Volume Forecast
U.S.A., Hospital Blood Banks Infectious Disease Screening Test Volume Forecast
U.S.A., Military Blood Banks Infectious Disease Screening Test Volume Forecast
U.S.A., All Market Segments Blood Typing And Grouping Reagent Market Forecast by Market Segment
U.S.A., All Market Segments Blood Typing And Grouping Reagent Market Forecast by Market Segment
U.S.A., Hospital Blood Banks Blood Typing And Grouping Reagent Market Forecast by Major Test
U.S.A., Community and Regional Blood Centers Blood Typing and Grouping Reagent Market Forecast By Major Test
U.S.A., Commercial/Private Laboratories Blood Typing and Grouping Reagent Market Forecast By Major Test
U.S.A., Plasma Fractionation Centers Blood Typing and Grouping Reagent Market Forecast By Major Test
U.S.A., Military Blood Banks Blood Typing And Grouping Reagent Market Forecast by Major Test
U.S.A., All Market Segments Infectious Disease Screening Reagent Market by Market Forecast Segment
U.S.A., All Market Segments Infectious Disease Screening Reagent Market by Market Forecast Segment
U.S.A., Community and Regional Centers Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Plasma Fractionation Centers Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Hospital Blood Banks Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Military Blood Banks Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Major Suppliers of Blood Typing And Grouping Reagents Estimated Sales And Market Shares
U.S.A., HIV/HTLV Blood Screening Market, Reagent Sales by Major Supplier
U.S.A., Hepatitis Blood Screening Market, Reagents Sales by Major Supplier
U.S.A., Hepatitis C Blood Screening Market, Reagent Sales By Major Supplier
U.S.A., HIV/Hepatitis C NAT Market, Reagent Sales By Major Supplier
U.S.A., West Nile Virus NAT Market, Reagent Sales by Major Supplier
U.S.A., CMV Blood Screening Market, Reagent Sales by Major Supplier
U.S.A., Syphilis Blood Screening Market, Reagent Sales by Major Supplier
Major Companies Developing or Marketing Blood Typing and Grouping Tests
Major Companies Developing or Marketing HLA Typing Tests
Major Companies Developing or Marketing AIDS Tests
Major Companies Developing or Marketing Hepatitis Tests
Major Companies Developing or Marketing CMV Tests
Major Companies Developing or Marketing Syphilis Tests
Major Companies Developing or Marketing Blood Bank Analyzers
Executive Summary Table: U.S.A., Total Blood Bank Test Volume and Reagent Sales Forecast by Test Category
U.S.A., Estimated Number of Inpatient and Ambulatory Surgeries
U.S.A., Facilities Performing Blood Bank Tests by Market Segment
U.S.A., Hospital Laboratories Performing Blood Bank Tests by Bed Size
U.S.A., Commercial/Private Laboratories Performing Blood Bank Tests by Annual Test Volume Forecast
U.S.A., Facilities Collecting Whole Blood And Plasma by Market Forecast Segment
U.S.A., Whole Blood and Plasma Collections By Market Forecast Segment
U.S.A., All Market Segments Blood Typing and Grouping Test Volume by Market Forecast Segment
U.S.A., All Market Segments Blood Typing And Grouping Test Volume Forecast
U.S.A., Hospital Laboratories Blood Typing and Grouping Test Volume Forecast
U.S.A., Community and Regional Blood Centers Blood Typing and Grouping Test Volume Forecast
U.S.A., Commercial/Private Laboratories Blood Typing and Grouping Test Volume Forecast
U.S.A., Plasma Fractionation Centers Blood Typing and Grouping Test Volume Forecast
U.S.A., Military Blood Banks Blood Typing and Grouping Test Volume Forecast
U.S.A., All Market Segments Infectious Disease Screening Test Volume Forecast By Market Segment
U.S.A., All Market Segments Infectious Disease Screening Test Volume Forecast
U.S.A., Community and Regional Centers Infectious Disease Screening Test Volume Forecast
U.S.A., Plasma Fractionation Centers Infectious Disease Screening Test Volume Forecast
U.S.A., Hospital Blood Banks Infectious Disease Screening Test Volume Forecast
U.S.A., Military Blood Banks Infectious Disease Screening Test Volume Forecast
U.S.A., All Market Segments Blood Typing And Grouping Reagent Market Forecast by Market Segment
U.S.A., All Market Segments Blood Typing And Grouping Reagent Market Forecast by Market Segment
U.S.A., Hospital Blood Banks Blood Typing And Grouping Reagent Market Forecast by Major Test
U.S.A., Community and Regional Blood Centers Blood Typing and Grouping Reagent Market Forecast By Major Test
U.S.A., Commercial/Private Laboratories Blood Typing and Grouping Reagent Market Forecast By Major Test
U.S.A., Plasma Fractionation Centers Blood Typing and Grouping Reagent Market Forecast By Major Test
U.S.A., Military Blood Banks Blood Typing And Grouping Reagent Market Forecast by Major Test
U.S.A., All Market Segments Infectious Disease Screening Reagent Market by Market Forecast Segment
U.S.A., All Market Segments Infectious Disease Screening Reagent Market by Market Forecast Segment
U.S.A., Community and Regional Centers Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Plasma Fractionation Centers Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Hospital Blood Banks Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Military Blood Banks Infectious Disease Screening Reagent Market Forecast By Test
U.S.A., Major Suppliers of Blood Typing And Grouping Reagents Estimated Sales And Market Shares
U.S.A., HIV/HTLV Blood Screening Market, Reagent Sales by Major Supplier
U.S.A., Hepatitis Blood Screening Market, Reagents Sales by Major Supplier
U.S.A., Hepatitis C Blood Screening Market, Reagent Sales By Major Supplier
U.S.A., HIV/Hepatitis C NAT Market, Reagent Sales By Major Supplier
U.S.A., West Nile Virus NAT Market, Reagent Sales by Major Supplier
U.S.A., CMV Blood Screening Market, Reagent Sales by Major Supplier
U.S.A., Syphilis Blood Screening Market, Reagent Sales by Major Supplier
