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Innovative Coagulation Testing Technologies and Emerging Markets

November 2012 | 650 pages | ID: I7CB287CFF9EN
Venture Planning Group

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This unique 650-page report contains 150 tables, and provides forecasts for 40 major procedures, as well as sales and market shares for reagent and instrument suppliers by country. Available by country and section. This comprehensive seven-country report is designed to help current suppliers and potential market entrants identify and evaluate major business opportunities emerging in the coagulation market during the next decade. The report explores business and technological trends in the US, five major European countries (France, Germany, Italy, Spain, UK) and Japan; provides estimates of the test volume, instrument placements and installed base, as well as sales and market shares of leading competitors; compares features of major analyzers; profiles leading market players; and identifies specific product and business opportunities facing instrument and consumable suppliers during the next ten years. The growing cost-containment pressures in major industrialized nations, coupled with continued technological advances in chromagenic substrates, monoclonal antibodies, immunoassays, molecular diagnostics, computers and laboratory automation will radically change the coagulation testing practice during the next ten years. New specific and sensitive markers of hemostasis will be increasingly used on automated instrumentation. Coagulation testing will also become more standardized, offering opportunities for quality control products and services. Moreover, continuing contraction of the hospital system and technological advances will facilitate decentralization of the coagulation testing closer to the patient, thus creating additional opportunities and challenges for suppliers.
INTRODUCTION

WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW

A. Major Routine and Special Coagulation Tests
  1. Introduction
  2. Activated Partial Thromboplastin Time (APTT)
  3. Alpha-2 Antiplasmin   4. Antithrombin III
  5. Bleeding Time
  6. D-Dimer
  7. Ethanol Flocculation Test 8. Euglobulin Lysis
  9. Factor Assays
    a. Introduction
    b. Factor II
    c. Factor V/Factor V Leiden
    d. Factor VII
    e. Factor VIII
    f. Factor IX
    g. Factor IXa
    h. Factor X (Stuart Factor)
    i. Factor Xa
    j. Factor XI
    k. Factor XII
    l. Factor XIII
  10. Fibrin Degradation Products
  11. Fibrinogen
  12. Heparin
  13. Hirudin
  14. Hypercoagulability and Thrombosis
  15. Lipoprotein a
  16. Plasmin
  17. Plasminogen
  18. Plasminogen Activator Inhibitor (PAI)
  19. Platelet Function Tests
  20. Platelet Aggregation
  21. Proteins C and S
  22. Prothrombin Fragment 1.2
  23. Prothrombin Time (PT)
  24. Reptilase Time
  25. Thrombin Time
  26. Tissue-Type Plasminogen Activator (t-PA)
  27. Von Willebrand's Factor
B. Instrumentation Review
  Introduction
  Benk Hemolab
  Benk TRT Thrombotimer
  Bio/Data MCA 310
  Bio/Data MCA 210
  Bio/Data PAP-4C D/4D/4C
  Cardiovascular Diagnostics COAG
  Diagnostica Stago STA Compact
  Diagnostica Stago STA-R
  Diagnostica Stago Star 4/8
  Helena Laboratories Cascade 480
  Helena Laboratories Cascade M
  Helena Laboratories PACKS-4
  Helena THOR
  Instrumentation Laboratory ACL 100 and 1000 series
  Instrumentation Laboratory ACL6000
  Instrumentation Laboratory ACL7000
  Instrumentation Laboratory ACL9000
  Instrumentation Laboratory Electra 1000C
  Instrumentation Laboratory Electra 1400C
  Instrumentation Laboratory Electra 1600/C
  Instrumentation Laboratory Electra 1800C
  Instrumentation Laboratory Futura
  ITC Hemochron 8000
  Roche Diagnostics CoaguChek
  Siemens BCS
  Siemens BCT
  Siemens BF II/Fibrintimer Series
  Sysmex CA-50
  Sysmex CA-500
  Sysmex CA-1500
  Sysmex CA-5000/CA-1000
  Sysmex CA-6000
  Sysmex CA-7000
  Teco Coatron II/Jr./AccuStasis 5000
  Trinity Biotech Amax CS190
  Trinity Biotech Amax CS400
  Trinity Biotech Coag-A-Mate Max
  Trinity Biotech KC 40, 4A, 1A Series
  Trinity Biotech MDA 180
  Trinity Biotech Coag-A-Mate MTX
  Trinity Biotech Coag-A-Mate RA4
  Trinity Biotech Coag-A-Mate XC/Plus
  Trinity Biotech Coag-A-Mate XM
C. Major in Vitro Diagnostic Technologies and Their Potential Applications
  1. Chromogenic Substrates
  2. Monoclonal and Polyclonal Antibodies
  3. Immunoassays
    a. Applications
    b. Technological Principle
    c. Enzyme Immunoassays (EIA)
      Overview
      ELISA
      EMIT
      Dot Immunobinding Assays
      Capillary Immunoassays
      Enzyme Amplification
      Electrochemical Immunoassay
    d. Fluorescent Immunoassays
      Fluorescence Polarization
      Time-Resolved Pulse Fluorescence
      Fluorescence Lifetime
    e. Latex Agglutination
    f. Immunoprecipitation
  4. Microcomputers
  5. Automation
  6. Robotics
  7. DNA Probes
    a. Overview
    b. Amplification Methods
      PCR
      Ligase Chain Reaction
      Branched DNA
      Q-Beta Replicase
      NASBA
      SDA
      3 SR
      HPA
      Two-Tiered System
      LAT
  8. Artificial Intelligence
  9. Dry Chemistry 10. Biosensors
D. Worldwide Market Overview
  1. Business Environment
  2. Market Structure
  3. Market Size and Growth
  4. POC Testing Market

FRANCE

A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers

GERMANY

A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers

ITALY

A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers

JAPAN

A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers

SPAIN

A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers
2UK
A. Executive Summary
B. Business Environment
C. Market Structure
D. Market Size, Growth and Major Suppliers

USA

A. Executive Summary
B. Business Environment
  1. Health Care Expenditures
  2. Cost Consciousness
  3. Industry Consolidation
  4. Managed Care
  5. Hospitals
  6. Admissions
  7. Length of Stay
  8. Industry Diversification
  9. Physician Demographics
  10. Population Aging
    a. Chronic Illnesses
    b. Disease Incidence
    c. Susceptibility to Iatrogenesis
    d. Multiple Illness Cases
  11. Laboratory Regulations
C. Market Structure
  1. Centralized Testing
    a. Hospitals
    b. Commercial laboratories
  2. Decentralized Testing
    a. Physician Offices/Group Practices
    b. Point-of-Care Testing
    c. Home/Self Testing
    d. Other Decentralized Testing Locations
D. Market Size, Growth And Major Suppliers

MAJOR PRODUCT DEVELOPMENT OPPORTUNITIES

DESIGN CRITERIA FOR DECENTRALIZED TESTING PRODUCTS

ALTERNATIVE MARKET PENETRATION STRATEGIES

A. Internal Development
B. Collaborative Arrangements
C. University Contracts
D. Distribution Strategies for Decentralized Testing Markets
  1. Marketing Approaches
  2. Product Complexity
  3. Customer Preference
  4. Established Suppliers
  5. Emerging Suppliers
  6. Major Types Of Distributors
  7. Market Segmentation

POTENTIAL MARKET ENTRY BARRIERS AND RISKS

A. Market Maturity
B. Cost Containment
C. Competition
D. Technological Edge and Limitations
E. Patent Protection
F. Regulatory Constraints
G. Decentralized Testing Market Challenges

COMPETITIVE ASSESSMENTS

Abbott
American Diagnostica
Avocet Medical
Axis-Shield
Beckman Coulter
Becton Dickinson
Bio/Data Corporation
Biosite
Chrono-Log
Corgenix Medical
Diagnostica Stago
Helena Laboratories
HYPEN BioMed
Instrumentation Laboratory
ITC
Nanogen
Roche
Siemens
Sienco
Sysmex
Thermo Fischer
Trinity Biotech
ZyCare

LIST OF TABLES

Major Companies Developing or Marketing Activated Clotting Time Tests
Major Companies Developing or Marketing APTT Tests
Major Companies Developing or Marketing Alpha-2 Antiplasmin Tests
Major Companies Developing or Marketing Antithrombin III Tests
Major Companies Developing or Marketing Bleeding Time Tests
Major Companies Developing or Marketing D-dimer Tests
Major Companies Developing or Marketing Factor Assays
Major Companies Developing or Marketing Fibrin Degradation Product Tests
Major Companies Developing or Marketing Fibrinogen Tests
Major Companies Developing or Marketing Heparin Tests
Major Companies Developing or Marketing Plasmin Tests
Major Companies Developing or Marketing Plasminogen Tests
Major Companies Developing or Marketing Plasminogen Activator Inhibitor Tests
Major Companies Developing or Marketing Platelet Aggregation Tests
Major Companies Developing or Marketing Protein C Tests
Major Companies Developing or Marketing Protein S Tests
Major Companies Developing or Marketing PT Tests
Major Companies Developing or Marketing Thrombin Time Tests
Major Companies Developing or Marketing TPA Tests
Major Companies Developing or Marketing Von Willebrand's Factor Tests
Worldwide, All Market Segments, Laboratories Performing Coagulation Tests By Country, 2010
Worldwide, All Market Segments, Total Coagulation Test Volume By Country, 2010-2020
Worldwide, All Market Segments, Total Coagulation Reagent Market By Country, 2010-2020
Worldwide, All Market Segments, Total Coagulation Instrument Market By Country, 2010-2020
Worldwide, All Market Segments, Total Coagulation Diagnostics Market By Country, 2010-2020
Executive Summary Table: France, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
France, Laboratories Performing Coagulation Tests By Market Segment, 2010
France, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
France, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
France, Hospital Laboratories Average Daily Test Volume, 2010
France, Commercial/Private Laboratories Average Daily Test Volume, 2010
France, Total Coagulation Test Volume By Market Segment, 2010-2020
France, All Market Segments Coagulation Test Volume, 2010-2020
France, Hospital Laboratories Coagulation Test Volume, 2010-2020
France, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
France, Coagulation Reagent Market By Market Segment, 2010-2020
France, Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
France, Coagulation Instrument Market By Market Segment, 2010-2020
France, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
France, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
France, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
France, Total Coagulation Diagnostics Market By Product Category, 2010-2020
France, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
Executive Summary Table: Germany, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
Germany, Laboratories Performing Coagulation Tests By Market Segment, 2010
Germany, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
Germany, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
Germany, Hospital Laboratories Average Daily Test Volume, 2010
Germany, Commercial/Private Laboratories Average Daily Test Volume, 2010
Germany, Physician Offices/Group Practice Average Daily Test Volume, 2010
Germany, Total Coagulation Test Volume By Market Segment, 2010-2020
Germany, All Market Segments Coagulation Test Volume, 2010-2020
Germany, Hospital Laboratories Coagulation Test Volume, 2010-2020
Germany, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
Germany, Physician Offices/Group Practices Coagulation Test Volume, 2010-2020
Germany, Coagulation Reagent Market By Market Segment, 2010-2020
Germany, Major Suppliers of Coagulation Reagents, Estimated Sales and Market Shares, 2010
Germany, Coagulation Instrument Market By Market Segment, 2010-2020
Germany, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
Germany, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
Germany, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
Germany, Total Coagulation Diagnostics Market By Product Category, 2010-2020
Germany, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
Executive Summary Table: Italy, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
Italy, Laboratories Performing Coagulation Tests By Market Segment, 2010
Italy, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
Italy, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
Italy, Hospital Laboratories Average Daily Test Volume, 2010
Italy, Commercial/Private Laboratories Average Daily Test Volume, 2010
Italy, Total Coagulation Test Volum By Market Segment, 2010-2020
Italy, All Market Segments Coagulation Test Volume, 2010-2020
Italy, Hospital Laboratories Coagulation Test Volume, 2010-2020
Italy, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
Italy, Coagulation Reagent Market By Market Segment, 2010-2020
Italy, Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
Italy, Coagulation Instrument Market By Market Segment, 2010-2020
Italy, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
Italy, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
Italy, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
Italy, Total Coagulation Diagnostics Market By Product Category, 2010-2020
Italy, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
Executive Summary Table: Japan, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
Japan, Laboratories Performing Coagulation Tests By Market Segment, 2010
Japan, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
Japan, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
Japan, Hospital Laboratories Average Daily Test Volume, 2010
Japan, Commercial/Private Laboratories Average Daily Test Volume, 2010
Japan, Total Coagulation Test Volume By Market Segment, 2010-2020
Japan, All Market Segments Coagulation Test Volume, 2010-2020
Japan, Hospital Laboratories Coagulation Test Volume, 2010-2020
Japan, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
Japan, Coagulation Reagent Market By Market Segment, 2010-2020
Japan, Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
Japan, Coagulation Instrument Market By Market Segment, 2010-2020
Japan, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
Japan, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
Japan, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
Japan, Total Coagulation Diagnostics Market By Product Category, 2010-2020
Japan, Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
Executive Summary Table: Spain, Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
Spain, Laboratories Performing Coagulation Tests By Market Segment, 2010
Spain, Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
Spain, Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
Spain, Hospital Laboratories Average Daily Test Volume, 2010
Spain, Ambulatory Care Centers Average Daily Test Volume, 2010
Spain, Commercial/Private Laboratories Average Daily Test Volume, 2010
Spain, Total Coagulation Test Volume By Market Segment, 2010-2020
Spain, All Market Segments Coagulation Test Volume, 2010-2020
Spain, Hospital Laboratories Coagulation Test Volume, 2010-2020
Spain, Ambulatory Care Centers Coagulation Test Volume, 2010-2020
Spain, Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
Spain, Coagulation Reagent Market By Market Segment, 2010-2020
Spain, Major Suppliers of Coagulation Reagents, Estimated Sales and Market Shares, 2010
Spain, Coagulation Instrument Market By Market Segment, 2010
Spain, Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
Spain, Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
Spain, Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
Spain, Total Coagulation Diagnostics Market By Product Category, 2010-2020
Spain, Major Suppliers of Coagulation Diagnostic Products, Estimates Sales and Market Shares, 2010
Executive Summary Table: U.K., Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
U.K., Laboratories Performing Coagulation Tests By Market Segment, 2010
U.K., Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
U.K., Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
U.K., Hospital Laboratories Average Daily Test Volume, 2010
U.K., Commercial/Private Laboratories Average Daily Test Volume, 2010
U.K., Total Coagulation Test Volume By Market Segment, 2010-2020
U.K., All Market Segments Coagulation Test Volume, 2010-2020
U.K., Hospital Laboratories Coagulation Test Volume, 2010-2020
U.K., Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
U.K., Coagulation Reagent Market By Market Segment, 2010-2020
U.K., Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
U.K., Coagulation Instrument Market By Market Segment, 2010
U.K., Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
U.K., Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
U.K., Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
U.K., Total Coagulation Diagnostics Market By Product Category, 2010-2020
U.K., Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010
Executive Summary Table: U.S.A., Total Coagulation Diagnostics Market By Market Segment and Product Category, 2010-2020
U.S.A., Laboratories Performing Coagulation Tests By Market Segment, 2010
U.S.A., Hospital Laboratories Performing Coagulation Tests By Bed Size, 2010
U.S.A., Commercial/Private Laboratories Performing Coagulation Tests By Annual Test Volume, 2010
U.S.A., Physician Offices/Group Practices Performing Coagulation Tests By Practice Size, 2010
U.S.A., Hospital Laboratories Average Daily Test Volume, 2010
U.S.A., Commercial/Private Laboratories Average Daily Test Volume, 2010
U.S.A., Physician Offices/Group Practices Average Daily Test Volume U.S.A., Total Coagulation Test Volume By Market Segment, 2010-2020
U.S.A., All Market Segments Coagulation Test Volume, 2010-2020
U.S.A., Hospital Laboratories Coagulation Test Volume, 2010-2020
U.S.A., Physician Offices/Group Practices Coagulation Test Volume, 2010-2020
U.S.A., Commercial/Private Laboratories Coagulation Test Volume, 2010-2020
U.S.A., Coagulation Reagent Market By Market Segment, 2010-2020
U.S.A., Major Suppliers of Coagulation Reagents Estimated Sales and Market Shares, 2010
U.S.A., Coagulation Instrument Market By Market Segment, 2010-2020
U.S.A., Major Suppliers of Coagulation Analyzers, Estimated Total Instrument Placements and Market Shares, 2010
U.S.A., Major Suppliers of Coagulation Analyzers, Estimated Placements and Installed Base By Supplier and Model, 2010
U.S.A., Major Suppliers of Coagulation Analyzers, Estimated Instrument Sales and Market Shares, 2010
U.S.A., Total Coagulation Diagnostics Market By Product Category, 2010-2020
U.S.A., Major Suppliers of Coagulation Diagnostic Products, Estimated Sales and Market Shares, 2010


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